All examples are fictional practice questions.
1. 1,000 mL over 8 hours. On a pump, rate = volume / time = 1,000 / 8 = 125 mL/h. By gravity, drops per minute = volume (mL) x drop factor (drops/mL) / time (minutes). With a 20 drops/mL giving set: 1,000 x 20 / 480 = 41.67, so 42 drops/min. With a 15 drops/mL set: 1,000 x 15 / 480 = 31 drops/min. With a 60 drops/mL microdrip set, drops/min equals mL/h: 125 drops/min.
2. A small-volume infusion. 100 mL over 30 minutes with a 20 drops/mL set: 100 x 20 / 30 = 66.67, so 67 drops/min.
3. When will it finish? 750 mL remain and the pump runs at 100 mL/h. Time = 750 / 100 = 7.5 hours, so an infusion checked at 08:00 finishes at about 15:30.
4. Maintenance fluid by weight. UK NICE guidance (CG174) suggests about 25 to 30 mL/kg/day of water for routine maintenance in adults. For a 70 kg patient that is 70 x 25 = 1,750 mL to 70 x 30 = 2,100 mL per 24 hours, or about 73 to 88 mL/h. Prescribing is the prescriber's decision; the calculation shows how the numbers are reached.
5. Anion gap. Sodium 140, chloride 104, bicarbonate 24 mmol/L: anion gap = 140 - (104 + 24) = 12 mmol/L, within the range often quoted, although reference values vary by laboratory.
Round drops per minute to whole drops, keep units on every line, and check the answer is sensible: a litre over eight hours should never come out at 400 drops a minute.